Education and Research system

Articles fromHBP students

Ms. Sayaka Suzuki, 5th year student, published a first author paper "Cell-to-cell interaction analysis of prognostic ligand-receptor pairs in human pancreatic ductal adenocarcinoma" in Biochemistry and Biophysics Reports.

Dr. SangJoon Lee, 2018 graduate, published a first author paper "AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence" in Nature (2021).

Ms. Asuka Ishihara, 5th year student, published a first author paper "Metabolic responses to polychromatic LED and OLED light at night" in Scientific Reports.

Mr. Arvin Lapiz Valderrama, 5th year student, published a first author paper "Pbp1 mediates the aberrant expression of genes involved in growth defect of ccr4Δ and pop2Δ mutants in yeast Saccharomyces cerevisiae" in Genes to Cells.

Mr. Thanasis Poullikkas, 3rd year student, published a co-author paper“In vitro and in silico molecular docking studies of Rheum emodi-derived diamagnetic SnO2 nanoparticles and their cytotoxic effects against breast cancer”in New Journal of Chemistry

Mr. Thanasis Poullikkas, 3rd year student, published a first author paper“Viroinformatics-Based Analysis of SARS-CoV-2 Core Proteins for Potential Therapeutic Targets”in MDPI Antibodies

Dr. Yuki Miura, 2017 graduate, published a first author paper“Generation of human striatal organoids and cortico-striatal assembloids from human pluripotent stem cells”in nature biotechnology

Mr. Lalhaba Oinam 5th year student(a First author paper) and Ms. Yen Xuan Ngo 4th year student(a co-author paper), published“Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging”in Aging Cell.

Mr. Kotaro Sakamoto, 5th year student, published a first author paper“Four-Types of IIT-Induced Group Integrity of Plecoglossus altivelis”in Entropy.

Dr. Le Khoa Tran Phuc, 2017 graduate, published a first author paper“Histone Acetyltransferase MOF Blocks Acquisition of Quiescence in Ground-State ESCs through Activating Fatty Acid Oxidation”in Cell stem cell.

Dr. Takato Honda, 2018 graduate, published a first author and a corresponding author paper “Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors With Altered Sleep Homeostasis and Dopamine D2R-mediated Sleep Reduction” in iScience.

Ms. Menghua Zhang, 5th year student, published a co-author paper“Isolation and structure-activity relationship studies of jacaranones: anti-inflammatory quinoids from the Cuban endemic plant Jacaranda arborea (Bignoniaceae)”in Tetrahedron Letters.

Dr. Takato Honda, 2018 graduate, published a co-author paper “Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need” in Scientific Reports.

Ms. Menghua Zhang, 5th year student, published a first author paper“Progressive changes in sleep and its relations to amyloid-β distribution and learning”in single App knock-in mice.

Ms. Sakura Eri B. Maezono, 5th year student,published a co-author paper“Accelerator-based boron neutron capture therapy for malignant glioma: a pilot neutron irradiation study using boron phenylalanine, sodium borocaptate and liposomal borocaptate with a heterotopic U87 glioblastoma model in SCID mice.”in International Journal of Radiation Biology.

Ms. Tram Anh Vu Nguyen, 3rd year student, published a co-author paper“Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling”in PNAS.

Ms. Sakura Eri B. Maezono, 5th year student, published a first author paper“Progressive changes in sleep and its relations to amyloid-β distribution and learning in single App knock-in mice.”in eNeuro.

Ms. Hoai Thu Le, 4th year student, published a co-author paper“Efficient production of large deletion and gene fragment knock-in mice mediated by genome editing with Cas9-mouse Cdt1 in mouse zygotes”in Methods.

Mr. Mitsunori Fujino, 2nd year student, published a first author paper“c-Maf deletion in adult C57BL/6J mice induces cataract formation and abnormal differentiation of lens fiber cells.”in Exp Anim. 2020 Jan 21. doi: 10.1538/expanim.19-0137. [Epub ahead of print].

Ms. Maho Kanai, 3rd year student, published a first author paper“Phenotypic analysis of mice carrying human-type MAFB p.Leu239Pro mutation.”in Biochem Biophys Res Commun. 2020 Mar 5;523(2):452-457. doi: 10.1016/j.bbrc.2019.12.033. Epub 2019 Dec 25.

Ms. Hoai Thu Le, 4th year student, published a first author paper“Generation of B6-Ddx4em1(CreERT2)Utr , a novel CreERT2 knock-in line, for germ cell lineage by CRISPR/Cas9,”in Genesis.

Dr. Sha Liang, 2017 graduate student, published a first author paper“Insights on the regulation of the MLL/SET1 family histone methyltransferases”in Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms.

Mr. Liu Chih Yao, 5th year student, published a first author paper“Copine-7 is required for REM sleep regulation following cage change or water immersion and restraint stress in mice”in Neuroscience Research.

Mr. Rikito Murata, 3th year student, published a Co-author paper“Tumor-derived Soluble CD155 Inhibits DNAM-1-mediated Antitumor Activity of Natural Killer Cells”in The Journal of experimental medicine.

Mr. Kotaro Sakamoto, 5th year student, published a first author paper“Finding continuity and discontinuity in fish schools via integrated information theory”in PLOS ONE.

Mr. Liu Chih Yao, 5th year student, published a co-author paper“Sleep architecture in adenosine A2A receptor- deficient mice.”in Sleep and Biological Rhythms.

Ms. Chia-Jung TSAI, 5th year student, published a first author paper“Sleep architecture in adenosine A2A receptor- deficient mice ”in Sleep and Biological Rhythms.

Ms. Sumire Matsumoto 5th year student and Ms. Asuka Ishihara 5th year student, published a Co-author paper“Association of wood use in bedrooms with comfort and sleep among workers in Japan: a cross-sectional analysis of the SLeep Epidemiology Project at the University of Tsukuba (SLEPT) study”in Journal of Wood Science.

Ms. Sumire Matsumoto, 5th year student, published a first author paper“Enhanced cortical responsiveness during natural sleep in freely behaving mice”in Scientific Reports.

Dr. Takato Honda, 2018 graduate, published a co-author paper “Effects of 3 Weeks of Water Immersion and Restraint Stress on Sleep in Mice” in Frontiers in Neuroscience.

Mr. Liu Chih Yao, 5th year student, published a first author paper“Effects of 3 weeks of water immersion and restraint stress on sleep in mice”in Frontiers in Neuroscience.

Mr. Lalhaba Oinam 4th year student(a First author paper) and Ms. Yen Xuan Ngo 3rd year student(a co-author paper), published“Chapter Two - Epidermal stem cell lineages” in Advances in Stem Cells and their Niches.

Mr. Kiyoshi Nagashima, 5th year student, published a first author paper “Behavior of ACRBP-deficient mouse sperm in the female reproductive tract”in Journal of Reproduction and Development.

Ms. Yu-Hsin Chang, 5th year student, published a first author paper “TRMT2A is a novel cell cycle regulator that suppresses cell proliferation”in Biochemical and Biophysical Research Communications.

Mr. Yuki Tsunakawa, 5th year student, published a first author paper “Mice harboring an MCTO mutation exhibit renal failure resembling nephropathy in human patients”in Experimental Animals.

Mr. Mustafa Korkutata, 5th year student, published a first author paper “Enhancing endogenous adenosine A2A receptor signaling induces slow-wave sleep without affecting body temperature and cardiovascular function.”in Neuropharmacology.

Ms. Anh Van Vo, 5th year student, published a first author paper “Selective DNAM-1 expression on small peritoneal macrophages contributes to CD4+ T cell costimulation”in Scientific Reports.

Ms. Kaushalya Kulathunga, 5th year student, published a first author paper “A Novel iRFP-Incorporated in vivo Murine Atherosclerosis Imaging System”in Scientific Reports.

Ms. Aya Takemura, 5th year student, published a first author paper “Sodium Polyanethol Sulfonate Modulates Natural Transformation of SigH-Expressing Staphylococcus aureus.”in Current Microbiology.

Dr. Takato Honda, 2018 graduate, published a first author paper “A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice” in Proceedings of the National Academy of Sciences of the United States of America (PNAS).

Mr. SangJoon LEE, 5th year student, published a first author paper “Influenza A Virus Infection Triggers Pyroptosis and Apoptosis of Respiratory Epithelial Cells through the Type I Interferon Signaling Pathway in a Mutually Exclusive Manner.”in Journal of Virology.

Mr. SangJoon LEE, 5th year student, published a co-author paper “Inhibition of Influenza Virus Infection by Lentinus edodes Mycelia Extract Through Its Direct Action and Immunopotentiating Activity”in Frontiers in Microbiology.

Mr. SangJoon LEE, 5th year student, published a co-author paper “Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma”in Oncogene.

Ms. Jung Yunshin,2018 graduate, published a first author paper“A context-specific circadian clock in adipocyte precursor cells modulates adipogenesis”in Adipocyte.

Mr. Rahul Sharma, 5th year student, published a co-author paper ”Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance”in Endocrinology.

Mr. Lalhaba OINAM, 4th year student, published a co-author paper “Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice”in Matrix Biology.

Mr. Toshiki Kato, 5th year student, published a first-author paper“SDF-1 improves wound healing ability of glucocorticoid-treated adipose tissue-derived mesenchymal stem cells.” in Biochemical and biophysical research communications.

Mr. Toshiki Kato, 5th year student, published a first-author paper “Elevated expression of Dkk-1 by glucocorticoid treatment impairs bone regenerative capacity of adipose tissue-derived mesenchymal stem cells.” in Stem cells and development.

Ms. Megumi Katoh, 5th year student, published a first-author paper “MafB is critical for glucagon production and secretion in mouse pancreatic α-cells in vivo.” in Molecular and Cellular Biology.

Ms. Megumi Katoh, 5th year student, published a co-author paper“Germline recombination in a novel Cre transgenic line, Prl3b1-Cre mouse.”in Genesis.

Mr. Akihiro Kuno, 5th year student, published a first author paper “Time-course transcriptome analysis of human cellular reprogramming from multiple cell types reveals the drastic change occurs between the mid phase and the late phase.” in BMC Genomics.

Ms. Toth Eszter, 5th year student, published a first author paper “Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(II)-dipeptide systems” in Dalton Transactions.

Ms. Toth Eszter, 5th year student, published a first author paper “Single-cell nanobiopsy reveals compartmentalization of mRNAs within neuronal cells.” in Journal of Biological Chemistry.

Mr. Bektik Emre, 5th year student, published a co-author paper“A Singular Role of IK1 Promoting the Development of Cardiac Automaticity during Cardiomyocyte Differentiation by IK1-Induced Activation of Pacemaker Current.”in Stem Cell Reviews and Reports.

Mr. Bektik Emre, 5th year student, published a first-author paper “Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes.” in Plos One.

Ms. Mayumi Abe, 5th year student, published a co-author paper“Regulation of cellular dynamics and chromosomal binding site preference of linker histone H1.0 and H1.X” in Molecular and cellular biology.

Ms. Mayumi Abe, 5th year student, published a first-author paper “Selective regulation of type II interferon-inducible genes by NPM1/nucleophosmin”in FEBS Letters.

Ms.Yuri Sakai, 5th year student, published a co-author paper “Polycomb repressive complex 2 facilitates the nuclear export of the influenza viral genome through the interaction with M1” in Scientific Reports.

Ms. Yuri Sakai, 5th year student, published a first author paper “Analysis by metadynamics simulation of binding pathway of influenza virus M2 channel blockers” in Microbiology and Immunology.

Mr. Kouta Niizuma, 5th year student, published a co-author paper “Cutting Edge: NKG2D Signaling Enhances NK Cell Responses but Alone Is Insufficient To Drive Expansion during Mouse Cytomegalovirus Infection” in The Journal of Immunology.

Mr. Takato Honda, 5th year student, published a co-author paper “Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapses” in npj Schizophrenia.

Ms. Yunshin Jung, 5th year student, published a first author paper“Isl1β Overexpression With Key β Cell Transcription Factors Enhances Glucose-Responsive Hepatic Insulin Production and Secretion.”in Endocrinology.

Ms. Yunshin Jung, 5th year student, published a co-author paper “Co-Chaperone BAG2 Determines the Pro-Oncogenic Role of Cathepsin B in Triple-Negative Breast Cancer Cells.”in Cell Report.

Mr. Takato Honda, 5th year student, published a co-author paper “Sleep/Wake Behaviors in Mice During Pregnancy and Pregnancy-Associated Hypertensive Mice” in SLEEP.

Ms. Kanako Oyama, 5th year student, published a co-author paper“PAPOLB/TPAP regulates spermiogenesis independently of chromatoid body-associated factors”in Journal of Reproduction and Development.

Ms. SHEN TZU-WEI, 5th year student, published a first author paper “TIF1β is phosphorylated at serine 473 in colorectal tumor cells through p38 mitogen-activated protein kinase as an oxidative defense mechanism.” in BBRC.

Ms. SHEN TZU-WEI, 5th year student, published a co-author paper “The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB” in Science Signaling.

Mr. Liu Yang, 5th year student, published a first-author paper “ATF7 ablation prevents diet-induced obesity and insulin resistance.” in Biochemical and Biophysical Research Communications.

Mr. Liu Yang, 5th year student, published a first-author paper “The transcription factor ATF7 mediates in vitro fertilization-induced gene expression changes in mouse liver.” in FEBS Open Bio.

Mr. Bektik Emre, 5th year student, published a co-author paper “A Singular Role of IK1 Promoting the Development of Cardiac Automaticity during Cardiomyocyte Differentiation by IK1–Induced Activation of Pacemaker Current” in Stem Cell Reviews and Reports.

HMr. Yuki Miura, 5th year student, published a first author paper “The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing” in Scientific Reports.

Mr. Lin Jianhuang, 5th year student, published a first author paper “Functional characterization and efficient detection of Nucleophosmin/NPM1 oligomers” in Biochemical and Biophysical Research Communications

Mr. Lin Jianhuang, 5th year student, published a first author paper “Efficient DNA binding of NF-κB requires the chaperone-like function of NPM1” in Nucleic Acids Research

Mr. Takuya Kikuchi, 5th year student, published a first author paper “Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression ” in Molecular Metabolism.

Mr. Takuya Kikuchi, 5th year student, published a co-author paper “Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system ” in Scientific Reports.

Mr. Takuya Kikuchi, 5th year student, published a co-author paper “Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr−/− mouse model ” in Scientific Reports.

Mr. Takuya Kikuchi, 5th year student, published a co-author paper “Salsalate activates brown adipose tissue in mice ” in Diabetes.

Ms. Dhouha Daassi, 5th year student, published a co-author paper “Optimisation of the critical medium components for better growth of Picochlorum sp. and the role of stressful environments for higher lipid production ” in Journal of the Science of Food and Agriculture.

Ms. Dhouha Daassi, 5th year student, published a co-author paper “Bioluminescence imaging of β cells and intrahepatic insulin gene activity under normal and pathological conditions ” in PLoS One.

Ms. Aya Takemura, 5th year student, published a co-author paper “Expression of a cryptic secondary sigma factor gene unveils natural competence for DNA transformation in Staphylococcus aureus ” in PLoS Pathogens.

Ms. Hashimoto Misuzu, 5th year student, published a co-author paper “Angiotensin II accelerates mammary gland development independently of high blood pressure in pregnancy-associated hypertensive mice ” in Physiological reports.

Mr. Yuki Miura, 5th year student, published a co-author paper “Machineries regulating the activity of the small GTPase Arf6 in cancer cells are potential targets for developing innovative anti-cancer drugs ” in Advances in Biological Regulation.

Mr. Le Tran Phuc Khoa, 5th year student, published a first author paper “Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells ” in PLoS One.

Mr. Le Tran Phuc Khoa, 5th year student, published a co-author paper “Comprehensive Identification of Krüppel-Like Factor Family Members Contributing to the Self-Renewal of Mouse Embryonic Stem Cells and Cellular Reprogramming ” in PLoS One.

Mr. Takato Honda, 4th year student, published a co-author paper “Forward-genetics analysis of sleep in randomly mutagenized mice ” in Nature.

Mr. Takato Honda, 4th year student, published a co-author paper “Identification of mutations through dominant screening for obesity using C57BL/6 substrings” in Scientific Reports.

Ms. Yu Ishikawa-Yamauchi, 4th year student, published a first author paper “Surfing and Swimming of Ejaculated Sperm in the Mouse Oviduct ” in Biology of Reproduction.

Ms. Yu Ishikawa-Yamauchi, 4th year student, published a co-author paper “Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing of Acrbp in the mouse ” in Proc. Natl. Acad. Sci. U.S.A..

Ms. Yu Ishikawa-Yamauchi, 4th year student, published a co-author paper “CABCOCO1, a novel coiled-coil protein With calcium-binding activity, is localized in the sperm flagellum ” in Molecular Reproduction and Development.

Mr. Takato Honda, 4th year student, published a first author paper and a corresponding author paper “Artificial Induction of Associative Olfactory Memory by Optogenetic and Thermogenetic Activation of Olfactory Sensory Neurons and Octopaminergic Neurons in Drosophila Larvae” in Frontiers in Behavioral Neuroscience.

Ms. Daassi Dhouha, 5th year student, published a first author paper “Differential expression patterns of MafB and c-Maf in macrophages in vivo and in vitro” in Biochemical and Biophysical Research Communications.

Ms. Misuzu Hashimoto, 4th year student, published a first author paper “Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System” in The Journal of Biological Chemistry.

Ms. Akihiro Kuno, 3rd year student, published a co-author paper “Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging” in Nature Protocols.

Mr. Kouta Niizuma, 3rd year student, published a first author paper “Identification and Characterization of CD300H, a New Member of the Human CD300 Immunoreceptor Family” in The Journal of Biological Chemistry.

Ms. Snoussi Kenza, 3rd year student, published a first author paper “Interaction of parvoviruses with the nuclear envelope” in Advances in Biological Regulation.

Mr. Takato Honda's first author paper has been selected as the Nature Asia “Paper of the Month”

Ms. Dinh Tra Thi Huong, 3rd year student, published a first author paper “Truncated Cables1 causes agenesis of the corpus callosum in mice” in Laboratory Investigation.

Mr. Takato Honda, 2nd year student, published a first author paper “Induction of Associative Olfactory Memory by Targeted Activation of Single Olfactory Neurons in Drosophila Larvae” in Scientific Reports.