The Ph.D. Program in Human Biology is a 5 year doctoral program integrating biological science, medicine, computational science, and materials science.

Education and Research system

2018/09/21
Ms. Aya Takemura, 5th year student, published a first author paper “Sodium Polyanethol Sulfonate Modulates Natural Transformation of SigH-Expressing Staphylococcus aureus.”in Current Microbiology. NEW
2018/09/14
Mr. SangJoon LEE, 5th year student, published a first author paper “Influenza A Virus Infection Triggers Pyroptosis and Apoptosis of Respiratory Epithelial Cells through the Type I Interferon Signaling Pathway in a Mutually Exclusive Manner.”in Journal of Virology.
2018/09/14
Mr. SangJoon LEE, 5th year student, published a co-author paper “Inhibition of Influenza Virus Infection by Lentinus edodes Mycelia Extract Through Its Direct Action and Immunopotentiating Activity”in Frontiers in Microbiology.
2018/09/14
Mr. SangJoon LEE, 5th year student, published a co-author paper “Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma”in Oncogene.
2018/06/26
Mr. Rahul Sharma, 5th year student, published a co-author paper ”Transgenic Mice Overexpressing SREBP-1a in Male ob/ob Mice Exhibit Lipodystrophy and Exacerbate Insulin Resistance”in Endocrinology.
2018/06/26
Mr. Lalhaba OINAM, 4th year student, published a co-author paper “Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice”in Matrix Biology.
2018/04/30
Mr. Toshiki Kato, 5th year student, published a first-author paper“SDF-1 improves wound healing ability of glucocorticoid-treated adipose tissue-derived mesenchymal stem cells.” in Biochemical and biophysical research communications.
2018/04/30
Mr. Toshiki Kato, 5th year student, published a first-author paper “Elevated expression of Dkk-1 by glucocorticoid treatment impairs bone regenerative capacity of adipose tissue-derived mesenchymal stem cells.” in Stem cells and development.
2018/04/30
Ms. Megumi Katoh, 5th year student, published a first-author paper “MafB is critical for glucagon production and secretion in mouse pancreatic α-cells in vivo.” in Molecular and Cellular Biology.
2018/04/30
Ms. Megumi Katoh, 5th year student, published a co-author paper“Germline recombination in a novel Cre transgenic line, Prl3b1-Cre mouse.”in Genesis.
2018/04/30
Mr. Akihiro Kuno, 5th year student, published a first author paper “Time-course transcriptome analysis of human cellular reprogramming from multiple cell types reveals the drastic change occurs between the mid phase and the late phase.” in BMC Genomics.
2018/04/30
Ms. Toth Eszter, 5th year student, published a first author paper “Exploring the boundaries of direct detection and characterization of labile isomers – a case study of copper(II)-dipeptide systems” in Dalton Transactions.
2018/04/30
Ms. Toth Eszter, 5th year student, published a first author paper “Single-cell nanobiopsy reveals compartmentalization of mRNAs within neuronal cells.” in Journal of Biological Chemistry.
2018/03/31
Mr. Bektik Emre, 5th year student, published a co-author paper“A Singular Role of IK1 Promoting the Development of Cardiac Automaticity during Cardiomyocyte Differentiation by IK1-Induced Activation of Pacemaker Current.”in Stem Cell Reviews and Reports.
2018/03/31
Mr. Bektik Emre, 5th year student, published a first-author paper “Single cell qPCR reveals that additional HAND2 and microRNA-1 facilitate the early reprogramming progress of seven-factor-induced human myocytes.” in Plos One.
2018/03/31
Ms. Mayumi Abe, 5th year student, published a co-author paper“Regulation of cellular dynamics and chromosomal binding site preference of linker histone H1.0 and H1.X” in Molecular and cellular biology.
2018/03/31
Ms. Mayumi Abe, 5th year student, published a first-author paper “Selective regulation of type II interferon-inducible genes by NPM1/nucleophosmin”in FEBS Letters.
2018/03/31
Ms.Yuri Sakai, 5th year student, published a co-author paper “Polycomb repressive complex 2 facilitates the nuclear export of the influenza viral genome through the interaction with M1” in Scientific Reports.
2018/03/31
Ms. Yuri Sakai, 5th year student, published a first author paper “Analysis by metadynamics simulation of binding pathway of influenza virus M2 channel blockers” in Microbiology and Immunology.
2018/03/31
Mr. Kouta Niizuma, 5th year student, published a co-author paper “Cutting Edge: NKG2D Signaling Enhances NK Cell Responses but Alone Is Insufficient To Drive Expansion during Mouse Cytomegalovirus Infection” in The Journal of Immunology.
2018/03/31
Mr. Takato Honda, 5th year student, published a co-author paper “Genetic interaction of DISC1 and Neurexin in the development of fruit fly glutamatergic synapses” in npj Schizophrenia.
2018/03/31
Ms. Yunshin Jung, 5th year student, published a first author paper“Isl1β Overexpression With Key β Cell Transcription Factors Enhances Glucose-Responsive Hepatic Insulin Production and Secretion.”in Endocrinology.
2018/03/31
Ms. Yunshin Jung, 5th year student, published a co-author paper “Co-Chaperone BAG2 Determines the Pro-Oncogenic Role of Cathepsin B in Triple-Negative Breast Cancer Cells.”in Cell Report.
2017/10/31
Ms. SHEN TZU-WEI, 5th year student, published a first author paper “TIF1β is phosphorylated at serine 473 in colorectal tumor cells through p38 mitogen-activated protein kinase as an oxidative defense mechanism.” in BBRC.
2017/10/31
Ms. SHEN TZU-WEI, 5th year student, published a co-author paper “The transcription factor MAFK induces EMT and malignant progression of triple-negative breast cancer cells through its target GPNMB” in Science Signaling.
2017/10/31
Mr. Liu Yang, 5th year student, published a first-author paper “ATF7 ablation prevents diet-induced obesity and insulin resistance.” in Biochemical and Biophysical Research Communications.
2017/10/31
Mr. Liu Yang, 5th year student, published a first-author paper “The transcription factor ATF7 mediates in vitro fertilization-induced gene expression changes in mouse liver.” in FEBS Open Bio.
2017/06/30
Mr. Bektik Emre, 5th year student, published a co-author paper “A Singular Role of IK1 Promoting the Development of Cardiac Automaticity during Cardiomyocyte Differentiation by IK1–Induced Activation of Pacemaker Current” in Stem Cell Reviews and Reports.
2017/03/24
Mr. Yuki Miura, 5th year student, published a first author paper “The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing” in Scientific Reports.
2017/01/19
Mr. Lin Jianhuang, 5th year student, published a first author paper “Functional characterization and efficient detection of Nucleophosmin/NPM1 oligomers” in Biochemical and Biophysical Research Communications
2017/01/19
Mr. Lin Jianhuang, 5th year student, published a first author paper “Efficient DNA binding of NF-κB requires the chaperone-like function of NPM1” in Nucleic Acids Research
2016/12/05
Mr. Takuya Kikuchi, 5th year student, published a first author paper “Intestinal CREBH overexpression prevents high-cholesterol diet-induced hypercholesterolemia by reducing Npc1l1 expression ” in Molecular Metabolism.
2016/12/05
Mr. Takuya Kikuchi, 5th year student, published a co-author paper “Hyperlipidemia and hepatitis in liver-specific CREB3L3 knockout mice generated using a one-step CRISPR/Cas9 system ” in Scientific Reports.
2016/12/05
Mr. Takuya Kikuchi, 5th year student, published a co-author paper “Absence of Elovl6 attenuates steatohepatitis but promotes gallstone formation in a lithogenic diet-fed Ldlr−/− mouse model ” in Scientific Reports.
2016/12/05
Mr. Takuya Kikuchi, 5th year student, published a co-author paper “Salsalate activates brown adipose tissue in mice ” in Diabetes.
2016/12/05
Ms. Dhouha Daassi, 5th year student, published a co-author paper “Optimisation of the critical medium components for better growth of Picochlorum sp. and the role of stressful environments for higher lipid production ” in Journal of the Science of Food and Agriculture.
2016/12/05
Ms. Dhouha Daassi, 5th year student, published a co-author paper “Bioluminescence imaging of β cells and intrahepatic insulin gene activity under normal and pathological conditions ” in PLoS One.
2016/12/05
Ms. Aya Takemura, 5th year student, published a co-author paper “Expression of a cryptic secondary sigma factor gene unveils natural competence for DNA transformation in Staphylococcus aureus ” in PLoS Pathogens.
2016/12/05
Ms. Hashimoto Misuzu, 5th year student, published a co-author paper “Angiotensin II accelerates mammary gland development independently of high blood pressure in pregnancy-associated hypertensive mice ” in Physiological reports.
2016/12/05
Mr. Yuki Miura, 5th year student, published a co-author paper “Machineries regulating the activity of the small GTPase Arf6 in cancer cells are potential targets for developing innovative anti-cancer drugs ” in Advances in Biological Regulation.
2016/12/05
Mr. Le Tran Phuc Khoa, 5th year student, published a first author paper “Visualization of the Epiblast and Visceral Endodermal Cells Using Fgf5-P2A-Venus BAC Transgenic Mice and Epiblast Stem Cells ” in PLoS One.
2016/12/05
Mr. Le Tran Phuc Khoa, 5th year student, published a co-author paper “Comprehensive Identification of Krüppel-Like Factor Family Members Contributing to the Self-Renewal of Mouse Embryonic Stem Cells and Cellular Reprogramming ” in PLoS One.
2016/12/05
Mr. Takato Honda, 4th year student, published a co-author paper “Forward-genetics analysis of sleep in randomly mutagenized mice ” in Nature.
2016/12/05
Mr. Takato Honda, 4th year student, published a co-author paper “Identification of mutations through dominant screening for obesity using C57BL/6 substrings” in Scientific Reports.
2016/12/05
Ms. Yu Ishikawa-Yamauchi, 4th year student, published a first author paper “Surfing and Swimming of Ejaculated Sperm in the Mouse Oviduct ” in Biology of Reproduction.
2016/12/05
Ms. Yu Ishikawa-Yamauchi, 4th year student, published a co-author paper “Biogenesis of sperm acrosome is regulated by pre-mRNA alternative splicing of Acrbp in the mouse ” in Proc. Natl. Acad. Sci. U.S.A..
2016/12/05
Ms. Yu Ishikawa-Yamauchi, 4th year student, published a co-author paper “CABCOCO1, a novel coiled-coil protein With calcium-binding activity, is localized in the sperm flagellum ” in Molecular Reproduction and Development.
2016/09/01
Mr. Takato Honda, 4th year student, published a first author paper and a corresponding author paper “Artificial Induction of Associative Olfactory Memory by Optogenetic and Thermogenetic Activation of Olfactory Sensory Neurons and Octopaminergic Neurons in Drosophila Larvae” in Frontiers in Behavioral Neuroscience.
2016/04/12
Ms. Daassi Dhouha, 5th year student, published a first author paper “Differential expression patterns of MafB and c-Maf in macrophages in vivo and in vitro” in Biochemical and Biophysical Research Communications.
2016/01/06
Ms. Misuzu Hashimoto, 4th year student, published a first author paper “Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System” in The Journal of Biological Chemistry.
2015/11/11
Ms. Akihiro Kuno, 3rd year student, published a co-author paper “Advanced CUBIC protocols for whole-brain and whole-body clearing and imaging” in Nature Protocols.
2015/10/02
Mr. Kouta Niizuma, 3rd year student, published a first author paper “Identification and Characterization of CD300H, a New Member of the Human CD300 Immunoreceptor Family” in The Journal of Biological Chemistry.
2014/08/07
Ms. Snoussi Kenza, 3rd year student, published a first author paper “Interaction of parvoviruses with the nuclear envelope” in Advances in Biological Regulation.
2014/06/30
Mr. Takato Honda’s first author paper has been selected as the Nature Asia “Paper of the Month”
2014/06/27
Ms. Dinh Tra Thi Huong, 3rd year student, published a first author paper “Truncated Cables1 causes agenesis of the corpus callosum in mice” in Laboratory Investigation.
2014/05/29
Mr. Takato Honda, 2nd year student, published a first author paper “Induction of Associative Olfactory Memory by Targeted Activation of Single Olfactory Neurons in Drosophila Larvae” in Scientific Reports.

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Ph.D. Program in Human Biology

School of Integrative and Global Majors (SIGMA),
the University of Tsukuba
1-1-1 Tennodai, Tsukuba, Ibaraki 305-8577 JAPAN
TEL: +81-29-853-7085,
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